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| Clinical effect observation of opioid-free laryngeal mask general anesthesia during cervical conization |
| Women’s Hospital of Nanjing Medical University (Nanjing Maternity and Child Health Care Hospital), Nanjing, Jiangsu Province, 210004 |
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Abstract To investigate the application effect of opioid-free laryngeal mask general anesthesia during cervical conization. Methods: A total of 60 patients with elective cervical conization in the hospital were selected and divided into group A (30 cases with opioid-free laryngeal mask in general anesthesia) and group B (30 cases with conventional opioid laryngeal mask in general anesthesia) by random number table metho from February 2022 to July 2022. The changes of mean arterial pressure (MAP) and heart rate (HR) of the patients before anesthesia induction (T0), 5 minutes after anesthesia induction (T1), when the laryngeal mask was inserted (T2), sliced (T3), and 5 minutes after the removal of the laryngeal mask (T4) were compared between the two groups. The application of vasoactive drugs during the operation, the pain score by visual analog scale (VAS) before returning to the ward, and 4h, 12h, and 24h after surgery, the adverse reactions rate, and postoperative recovery situation of the patients in the two groups were counted. Results: There was no significant difference in the MAP value of the patients in group A between T1-4 and T0 (P＞0.05). The HR value of the patients in group A at T1-3 was significantly lower than that at T0 (P＜0.05). The MAP and HR values of the patients in group B at T1-3 were significantly lower than that at T0 (P＜0.05). The MAP value of the patients in group A at T1-3 was significantly higher than that of the patients in group B (P＜0.05). No urapidil was used in the patients in the two groups. The rate of ephedrine used (0 cases) of the patients in group A was significantly lower than that (23.3%) of the patients in group B (P＜0.05). The rate of atropine used (16.7%) of the patients in group A had no significantly different from that (13.3%) of the patients in group B (P＞0.05). There were no significant differences in the VAS scores of the patients at all time after surgery between the two groups (P＞0.05). The incidences of hypotension, and nausea and vomiting (3.3% and 3.3%) of the patients in group A were significantly lower than those (23.3%, 26.7%) of the patients in group B. The recovery time of directional force (9.6±2.7min), the stay time in resuscitation room (21.3±6.4min), and the time to the first anal exhaust (8.9±2.7h) of the patients in group A were significantly shorter than those (20.8±4.0min, 38.6±8.0min, and 15.8±3.5h) of the patients in group B (all P＜0.05). Conclusion: Opioid-free laryngeal mask general anesthesia used during cervical conization has the same effect as the conventional opioid anesthesia, but which has more stable intraoperative circulation, lower incidences of hypotension, and nausea and vomiting, and faster postoperative recovery.
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