To investigate the effects of cognitive and behavioral intervention of family caregivers for early postpartum primiparas on the breastfeeding of the primiparas. Methods: 104 primiparas who would gave birth were selected and were divided into study group(n=52)and control group(n=52)by random number table method between February 2020 and February 2021. The primiparas in the control group were given routine early postpartum nursing, and the primiparas in the study group were given routine early postpartum nursing and their family caregivers with cognitive and behavioral intervention. The breastfeeding self-efficacy, breastfeeding quality, quality of life, and postpartum psychological evaluative score of the primiparas were compared between the two groups. Results: The scores of breastfeeding self-efficacy(48.72±1.32 points)and inner activity(24.82±4.45 points)of the primiparas in the study group were significantly higher than those(47.33±1.25 points and 20.92±4.24 points)of the primiparas in the control group. The scores of breastfeeding quality, such as(feeding preparation)(14.27±1.73 points), feeding process(12.89±2.72 points)，and feeding result(13.81±2.06 points)of the primiparas in the study group were significantly higher than those(12.96±1.69 points, 11.82±1.83 points, and 12.37±0.71 points)of the primiparas in the control group. Three months after delivery, the quality of life score of the primiparas in the study group was significantly higher than that of the primiparas in the control group, and the scores(41.75±3.54 points and 41.52±3.43 points)by Self-rating Depression Scale(SDS)and Self-rating Anxiety Scale(SAS)of the primiparas in the study group were significantly lower than those(45.36±4.99 points and 46.02±6.02 points)of the primiparas in the control group(all P＜0.05). Conclusion: The cognitive and behavioral intervention of family caregivers for early postpartum primiparas can enhance the breastfeeding efficacy and quality, and can improve the quality of life and postpartum psychology of the primiparas.