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| The situation of small intestine bacterial overgrowth and the adverse pregnancy outcomes of women with gestational diabetes mellitus |
| The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, 450052 |
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Abstract To investigate the situation of small intestine bacterial overgrowth (SIBO) and the adverse pregnancy outcomes of pregnant women with gestational diabetes mellitus (GDM). Methods：98 pregnant women with GDM were randomly selected in observation group, and 49 healthy pregnant women were selected in control group from January 2018 to January 2019. The women in both groups were given hydrogen/methane breath test to observe the situation of SIBO. The pregnancy outcomes of the women were compared between the two groups. Results: The incidence of SIBO (34 cases, 34.7%) of the women in the observation group was significantly higher than those (7 cases, 14.3%) of the women in the control group. The incidences of hydramnios (9.2%), preterm birth (10.2%), and fetal distress (14.3%) of the women in the observation group were significantly higher than those (2.0%, 4.1%, and 6.1%) of the women in the control group (all P＜0.05). In the observation group, the rates of premature birth (20.6%), polyhydramnios (17.7%), and fetal distress (26.5%) of the women with positive SIBO were significantly higher than those (4.7%, 4.7%, and 7.8%) of the women with negative SIBO (all P＜0.05). Conclusion: SIBO may be associated with GDM of the pregnant women, hydrogen/methane breath test can be used for detecting SIBO of the women, and the women with positive SIBO should be treated actively.
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