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| Correlation between the blood glucose control level of pregnant women with gestational diabetes mellitus and their pregnancy outcomes |
| Nanjing Maternal and Child Health Care Hospital, Nanjing, Jiangsu Province, 210000 |
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Abstract To explore the relationship between the levels of blood glucose control of pregnant women with gestational diabetes mellitus (GDM) and their pregnancy outcomes. Methods: 180 pregnant women with GDM were selected and were divided into group A (84 with good blood glucose control) and group B (96 women with bad blood glucose control) according to the blood glucose control situation of the women during whole pregnancy. And 90 healthy pregnant women were selected in group C. The pregnancy and neonatal outcomes of the women in the three groups were recorded, and the correlation between blood glucose control level of the women with GDM and their pregnancy outcomes was analyzed. Results: The incidences of pregnancy-induced hypertension, premature delivery, polyhydramnios, cesarean section, premature rupture of membranes, and intrahepatic cholestasis of pregnancy of the women in group B were significantly higher than those of the women in group A and in group C (P＜0.05), and there were no significant differences in the incidences of postpartum hemorrhage and postpartum infection of the women among the three groups (P＞0.05). The incidences of perinatal fetal asphyxia, fetal distress, macrosomia, fetal growth restriction, neonatal asphyxia, neonatal hypoglycemia, neonatal bilirubin levels, high or low birth weight of newborns, neonatal pneumonia, and neonatal polycythemia disease of the women in group B were significantly higher than those of the women in group A and group C (P＜0.05), there were no significant differences in the incidences of perinatal stillbirth and the birth defects among the three groups (P＞0.05). Multivariate logistic stepwise regression analysis showed that in pregnant women with GDM, the rate of premature rupture of membrane in group B was 1.214 times higher than that in group A, the rate of intrahepatic cholestasis of pregnancy in group B was 3.046 times higher than that in group A, the rate of premature delivery in group B was 1.178 times higher than that in group A, the rate of macrosomia in group B was 7.267 times higher than that in group A, the rate of fetal growth restriction in group B was 1.219 times higher than that in group A, and the rate of neonatal hypoglycemia in group B was 3.057 times higher than that in group A. Conclusion: Poor blood glucose control of the pregnant women with GDM will lead to the high risk of their adverse pregnancy outcomes and perinatal outcomes.
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