|
|
|
| Correlation between the hormonal levels of ovarian function of women after curettage of missed abortion and their infertility caused by intrauterine adhesions |
| The Second Hospital of Traditional Chinese Medicine of Jiangsu Province, Nanjing, Jiangsu Province,210000 |
|
|
|
|
Abstract To observe the correlation between the ovarian function of women after curettage of missed abortion and their infertility caused by intrauterine adhesions infertility. Methods: The clinical data of 180 women with missed abortion after curettage from January 2018 to October 2019 were analyzed retrospectively. According to the results of followed up of the women after curettage, these women were divided group A (20 women with infertility due to intrauterine adhesions) and group B (160 women without infertility due to intrauterine adhesions). The levels of the ovarian function indicators, such as follicle-stimulating hormone (FSH), luteinizing hormone (LH), testosterone (T), and estradiol (E2), of the women in the two groups were detected in 2-3 months after curettage. The correlation between the ovarian function of the women after curettage of missed abortion and their infertility caused by intrauterine adhesions was analyzed by regression analysis. Receiver operating characteristic (ROC) curve was drawn to analyze the value of the hormone’s levels of the ovarian function for predicting infertility caused by intrauterine adhesion. Results: The level of E2 of the women in group A was significantly lower than that of the women in group B, but the levels of FSH, LH, and T of the women in group A were significantly higher (all P<0.05). Logistic regression analysis showed that the FSH, LH, T and E2 levels of the women in group A affected their infertility caused by intrauterine adhesion after curettage (OR>1, P<0.05). ROC curve was drawn based on the test variables of the levels of FSH, LH, T, and E2, and the results showed that the AUC of FSH level, LH level, T level, E2 level, or the combined detection of the FSH, LH, and T levels for predicting infertility were 0.965, 0.878, 0.943, 0.994, and 0.971, respectively. Conclusion: The hormonal levels of ovarian function of the women with missed abortion after curettage have certainly relevent to their infertility caused by intrauterine adhesions. In order to reduce the infertility caused by intrauterine adhesion, regular monitoring of ovarian function should be conducted in the women who want pregnancy after curettage of missed abortion, and should be reasonablely intervene their low expression level of E2 and high expression levels of FSH, LH, and T.
|
|
|
|
|
|
|
|
|
