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| Research progress of the expectant and medical treatment of endometrial polyps |
| The Sixth People’s Hospital, Shanghai Jiao Tong University School, Shanghai, 200233 |
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Abstract Endometrial polyps (EP) is a common gynecological disease. The treatment of EP depends on the symptoms, the risk of malignancy, and the fertility problems of the patients. Transcervical resection of polyp (TCRP) is the recommended surgical treatment. Expectant or medical conservative treatment may be conducted on the asymptomatic women with perimenopause. Hormone drugs can inhibit the occurrence of EP after TCRP. The drugs, commonly such as progesterone and combined oral contraception, have the effect of short-term prevention of EP recurrence, which can be applied to those patients with fertility requirements. And LNG-IUS is more suitable for the EP patients without fertility requirements, which can control the endometrial proliferative polyps and can reduce the incidence of EP occurrence of the patients during tamoxifen used. Tibolone can inhibit the development of endometrial polyps of the women in menopause. Gestrinone, gonadotropin-releasing hormone agonists, letrozole, and mifepristone can all relieve endometrial polyps of the women in short-term, but EP is prone to recurrence after stopping these drugs, and these drugs need to be considered in both the effectiveness of the disease controlled and the side effects.
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