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| Safety analysis of autologous blood prepared of high-risk pregnant women |
| Drum Tower Hospital Affiliated to Nanjing University Medical School, Nanjing, Jiangsu Province, 210008 |
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Abstract To investigate the safety of autologous blood prepared of high-risk pregnant women. Methods: A total of 184 pregnant women hospitalized for expectant delivery due to high-risk pregnancy were selected as study subjects from January 2018 to December 2019. These women were randomly divided into study group (women with autogenous blood prepared before birth) and control group (women without autogenous blood prepared before birth). The blood loss during delivery of the women, and the weight and body length of the newborns were compared between the two groups. The values of hemoglobin (Hb), hematocrit (HCT), platelet count (PLT), blood pressure, pulse, and oxygen saturation of the women in the study group in 1 week before autogenous blood prepared and before delivery were observed. Results: There was no statistically significant difference in the Hb value (118.8 ± 8.5 g/L vs. 121.2 ± 9.9 g/L) of the women before delivery between the two groups (P=0.06). In the study group, there were no significant differences in the values of HCT, Hb, and PLT of the women within 1 week before autogenous blood prepared and before delivery (P>0.05). In the study group, the value of systolic blood pressure (112.2±8.5 mmHg) of the women before autogenous blood prepared was significantly higher than that (110.1±8.0mmHg) after autogenous blood prepared (P=0.0632), and the value of diastolic blood pressure (70.8±7.1 mmHg) of the women before autogenous blood prepared was significantly higher than that (69.1±7.8) after autogenous blood prepared (P=0.1027). In the study group, the values of pulse and oxygen saturation of the women before autogenous blood prepared had no significant different from those after autogenous blood prepared (P>0.05). Conclusion: It is safe to use autologous blood prepared of the high-risk pregnant women without the adverse reaction related to blood transfusion occurrence. In the hospital clinic, the rate of blood transfusion of the high-risk pregnant women is high, so autologous blood prepared of these women should be conducted after comprehensive evaluation of their specific situation.
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