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| The effect of levonorgestrel-releasing intrauterine system for treating women with dysmenorrhea because of endometriosis and its influence on their quality of life |
| 1.Tiantai Branch of Zhejiang Provincial People's Hospital, Zhejiang Province, 317200; 2. Zhejiang Provincial People’s Hospital, People's Hospital Affiliated to Hanhzhou Medical College |
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Abstract To investigate the effectiveness of levonorgestrel-releasing intrauterine system (LNG-IUS) for treating women with dysmenorrhea because of endometriosis, and to study the improvement of the life quality of the women. Methods: The women with dysmenorrhea because of endometriosis were included and were inserted LNG-IUS for treatment. The visual analogue scales (VAS), life quality score, the CA125 level of the women before LNG-IUS inserted, 3, 6, 9, and 12 months after LNG-IUS inserted were recorded. The situations of adverse reactions of the women were also recorded during followed up. Results: A total of 85 women were enrolled, and in which, there were 4 women had been abandoned treatment due to adverse reactions within the first 3 months of treatment. 81 women were followed up for 12 months. After treatment, VAS score of menstrual period of the women decreased from 6.43 points to 2.08 points, VAS score of sexual pain of the women decreased from 5.14 points to 1.91 points, and VAS score of non-periodic pelvic pain of the women decreased from 5.84 points to 1.82 points. The score of life quality of the women increased significantly, and the CA125 level of the women decreased significantly after treatment. The most common adverse reaction was the change of menstrual patterns. Conclusion: LNG-IUS inserted for treating women with dysmenorrhea because of endometriosis has better effectiveness, which can effectively improve life quality of the women. The systemic adverse reaction of LNG-IUS needs to be sufficient communicated with the women for improving their tolerability of LNG-IUS.
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