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| Efficacy of severe intrauterine adhesiolysis of patients evaluated by three-dimensional energy Doppler ultrasonography |
| 1. Wenzhou Third Clinical College of Wenzhou Medical University, Wenzhou People's Hospital, Zhejiang Province，325000; 2. The First Affiliated Hospital of Wenzhou Medical University |
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Abstract To investigate the effectiveness of severe intrauterine adhesiolysis for treating patients with severe intrauterine adhesions (IUA) evaluated by threedimensional energy Doppler ultrasonography parameter, and to study the value of ultrasonography for predicting the recurrence of IUA. Methods: 126 patients with severe IUA who underwent intrauterine adhesiolysis were selected as the research subjects from January 2018 to January 2020. According to whether postoperative adhesions recurred, these patients were divided into group A (patients without adhesions recurrence) and group B (patients with adhesions recurrence). All of The patients were given three-dimensional energy Doppler ultrasonography examination before and after intrauterine adhesiolysis. The ultrasonography parameter and the recurrence of IUA of the patients before and after treatment were compared, and the predictive value of ultrasonography parameter for intrauterine adhesion recurrence was analyzed. Results: The values of endometrial volume (EV), vascular index (VI), blood flow index (FI), and vascular blood flow index (VFI) of the patients with cured and effectiveness after treatment evaluated by uterine morphology were significant higher than those before treatment (P<0.001), while which of the patients with invalid treatment evaluated by uterine morphology had no significant different from the patients before treatment (P>0.05). Within 12 months after treatment, the recurrence rate of intrauterine adhesions of these patients was 23.7%. The endometrial VI, FI, and VFI values of the patients in group A were significant higher than that of the patients in group B (P<0.05), but there was no significant difference in endometrial EV value of the patients between group A and B (P>0.05). After treatment, the endometrial FI and VFI values had some predictive values for the recurrence of intrauterine adhesions (P<0.05), and the VFI value had the better predictive effect, while VI value had no predictive effect for the recurrence of intrauterine adhesions (P>0.05). Conclusion: The endometrial parameters by three-dimensional energy Doppler ultrasonography can better evaluate the therapeutic effect of intrauterine adhesiolysis, and can predict the risk of recurrence of intrauterine adhesions.
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