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| Pregnancy outcomes of infertility women with endometriosis treated by laparoscopic minimally invasive surgery and its influence factor |
| Luzhou Maternal and Child Health Care Hospital, The Second People's Hospital of Luzhou, Luzhou, Sichuan Province, 646000 |
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Abstract To analyze the pregnancy outcome of infertility women with endometriosis treated by laparoscopic minimally invasive surgery, and to study its influence factors. Methods: The clinical data of 116 infertility women with endometriosis treated by laparoscopic minimally invasive surgery were collected from January 2016 to January 2019. The pregnancy outcomes of these women were statistics analyzed. Logistic regression model was used to analyze the risk factors affecting the pregnancy outcomes of these women. Results: Among the 116 women, there were 76 women with pregnancy after surgery, which included 59 women with natural pregnancy and 17 women with pregnancy after assisted reproductive. The pregnancy rate of the women with r-AFS stage Ⅰ, Ⅱ, Ⅲ, and Ⅳ were 64.7%, 62.5%, 72.0%, and 56.3%, respectively. The pregnancy rate of the women with EFI score ≤4 points, 5-8 points, and 9-10 points were 38.1%, 63.0%, 79.6%, respectively. In 76 women with pregnancy, there were 49 (64.5%) women with live born infants, 11(14.5%) women with ectopic pregnancy, 15(19.7%) women with spontaneous abortion, and 1(1.3%) woman with stillbirth. There was no significant difference in pregnancy outcomes among the women with different stages of R-AFS (P＞0.05). The rate of normal pregnancy outcomes of the women with high EFI score and postoperative GnRH-A treatment was significant higher (P＞0.05). Multivariate analysis had showed that ≥35 years old, ≥2 times of intrauterine operation, no postoperative GnRH-a treatment, low EFI score, and duration of infertility ≥3 years were the risk factors of adverse pregnancy outcomes of infertility women with EMT after laparoscopic minimally invasive surgery (P＜0.05). Conclusion: Laparoscopic minimally invasive surgery for treating infertility women with endometriosis has an ideal clinical effect for improving their pregnancy outcomes. Age, the number of intrauterine operation, postoperative GnRH-a treatment, EFI score, and duration of infertility are the risk factors of their adverse pregnancy outcomes.
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