|
|
|
| Clinical comparison of propofol combined with nalbuphine, dezocine, or sufentanil for analgesia in painless induced abortion |
| 1. The Second People's Hospital of Huai 'an, Jiangsu Province, 223001；2.Nanjing Jiangning Hospital；3.Huai 'an Hospital of Traditional Chinese Medicine |
|
|
|
|
Abstract To compare the clinical effect of propofol combined with nalbuphine, dezocine, or sufentanil for analgesia in painless induced abortion. Methods: From January 2019 to June 2020, 156 pregnant women who wanted painless induced abortion during the first trimester of pregnancy were selected and were divided into three groups by random number table, which included group A (52 women accepted propofol combined with dezocine for analgesia), group B(52 women accepted propofol combined with nalbuphine for analgesia), and group C (52 women accepted propofol combined with sufentanil for analgesia). The values of systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), and blood oxygen saturation (SpO2) of the women at different times, anesthesia effect, and adverse reactions rate of the women were compared among the three groups. Results: The values of SBP, DBP, and SpO2 of the women before administration of anesthesia drug and when eyelash reaction disappeared in group B were significant higher than those of the women in group A and group C (P＜0.05). The dosage of propofol (113.7±10.3mg) and awaken time (3.35±0.4min) of the women in group B were significant less than those (132.2±21.5mg and 7.1±1.3 min) of the women in group A, and those (129.4±15.7mg and 5.8±0.9min) in group C (P＜0.05). The total incidence of adverse reaction (19.2%) of the women in group B was significant lower than that (57.7%) of the women in group A, and that (53.9%) of the women in group C (P＜0.05). Conclusion: The efficacy and safety of propofol combined with nalbuphine for anesthesia in painless induced abortion are better than those of propofol combined with dezocine or sufentanil.
|
|
|
|
|
|
|
|
|
