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Abstract To analyze the effects and prognosis of different options for treating pregnant women with cesarean scar pregnancy (CSP). Methods: The clinical data of 102 women with CSP from January 2019 to June 2020 were collected retrospectively. Among them, 20 women in group A were given methotrexate combined with curettage, 29 women in group B were given tranvaginal scar pregnancy removal combined with uterine muscle wall repair, 30 women in group C were given uterine artery perfusion embolization combined with curettage, and 33 women in group D were given laparoscopic scar pregnancy removal combined with uterine muscle wall repair. The operation time, hospital stay, intraoperative blood loss, treatment success rate, the β-human chorionic gonadotropin (β-HCG) level before and on the first and the second day after operation, the prognostic indicators, such as the time of vaginal bleeding, the time of β-HCG level returned to normal, the time of disappearance of scar mass，the time of menstrual recovery, and the rates of adhesion of uterine cavity and the complications of women in the four groups were statistical analyzed. Results: The treatment success rate of the women in group A was the lowest, the operative time of the women in group B and C was the longest, the hospital stay of the women in group A and C was the longest, and the intraoperative blood loss of the women in group A and C was the least (P<0.05). After treatment, the level of β-HCG of the women in the four groups has decreased significantly (P<0.05), but that of the women in group A was significant higher than that of the women in the other three groups (P<0.05). The vaginal bleeding time of the women in group A and C was the longest, the time of β-HCG level returned to normal and the disappearance time of scar mass of the women in group A were the longest, the time of menstruation recovery of the women in group C was the longest, and the proportion of intrauterine adhesion of the women in group A was the lowest (P<0.05). There was no difference in the total incidence of postoperative complications of the women among the four groups (P>0.05). Conclusion: The treatment success rate, the hospitalization time, theβ-HCG level on the first and second day after operation, and the time ofβ-HCG level returned to normal of the pregnant women with CSP treated by laparoscopic scar pregnancy lesion removal combined with uterine muscle wall repair are all significant better than those of the women treated by other methods, and which have not increased postoperative complication occurrence.
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