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| Effect of sufentanil prophylactic analgesia on VAS score and stress index of women who experienced cesarean section |
| Shaanxi Nuclear Industry 2155 Hospital, Xianyang, Shaanxi Province,712000 |
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Abstract To observe the effect of sufentanil for preventive analgesia during cesarean section, and to study its influence on the maternal analgesic VAS score, and the levels of blood glucose and cortisol. Methods: From February 2017 to June 2018, 80 women with cesarean section were divided into study group and control group (40 cases in each group). The stress indexes, such as hemodynamic, blood glucose and cortisol, and VAS scores during perioperative period of women were compared between the two groups. Results: MAP (87.47±3.75mmHg), HR (81.0±5.1 times/min), blood glucose level (4.23±0.95mmol/L), cortisol level (362.45±16.24ng/ml), and TNF-αlevel (23.18±4.27pg/ml) of women in the study group at 2 hours after surgery were all significant lower than those of women in the control group (P＜0.001), but there was no significant difference in postoperative sedation effect (Ramsay score) of women between the two groups. VAS scores of women in the study group at 4 and 12 hours after surgery were 2.4±1.1 points and 1.5±0.7 points, which were significant lower than those of women in the control group (P＜0.001). Conclusion: The effect of sufentanil for preventive analgesia during cesarean section is good, and the stress response of parturient is less, so it has good clinical application value.
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