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| The application of thrombus elastic map in monitoring coagulation function during cesarean section of women with obstetrical hemorrhagic diseases |
| People's Hospital of China Medical University, Shenyang, Liaoning Province, 110016 |
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Abstract To evaluate the effect of thrombus elastography (TEG)) in monitoring coagulation function during cesarean section of women with obstetrical hemorrhagic diseases. Methods: From April 2017 to March 2019, 55 women with hemorrhagic diseases during pregnancy (preeclampsia, placenta previa, or pregnancy complicated with obesity, etc.) who had undergone optional cesarean section were included in observation group. Another 60 normal women who had undergone cesarean section were selected in control group during the same period. Before and 24 hours after operation, comparison was made between the two groups of the values of four coagulation indexes, such as fibrinogen (FIB), prothrombin time (PT), thrombin time (TT), and partial thrombin time (APTT), TEG monitored blood coagulation reaction time (R value), blood clot formation time (K value), coagulation Angle (Angle), maximum blood clot strength (MA), and blood coagulation composite index (CI). Results: The values of PT and APTT of women in the two groups had decreased significantly 24 hours after operation (P＜0.05), but the values of FIB and TT of women in the two groups had no change after operation (P>0.05). There was no significant different in the values of PT, TT, APTT, and FIB of women between the two groups (P>0.05). The R and K values of women in the two groups had increased significantly, but CI value had decreased significantly after operation (P＜0.05). The values of α angle and MA had no change after operation (P>0.05). There was no significant difference in the values of R, K and MA of women between the two groups before and 24 hours after operation, but the α angle and CI values of women in the observation group were significant lower than those of women in the control group (P＜0.05). Conclusion: TEG has more advantages in monitoring coagulation function during cesarean section of women with hemorrhagic disease, and can accurately evaluate the generalize of coagulation and can analyze the causes of hypocoagulation of women, which is beneficial to early intervention and to avoid the influence of abnormal coagulation on the prognosis of women.
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