|
|
|
| Analysis of the normal value of fetal NT value of pregnant women with normal single-fetus pregnancy during the first trimester of pregnancy in Wuhan area |
| Wuhan Children's Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology（Wuhan Maternal and Child Health Care Hospital）, Hubei Province, 430000 |
|
|
|
Abstract To explore the normal range of fetal NT value of pregnant women with normal single-fetus pregnancy during the first trimester of pregnancy in Wuhan area, and to study the fetal NT value correlation with gestational weeks, maternal age, and fetal gender. Methods: 3617 pregnant women with normal single-fetus pregnancy during 11-13 gestational weeks from January 2013 to December 2017 were selected in this study continually. Fetal NT values of these women were measured by ultrasound. The normal reference range of NT value of normal single fetus was established. The differences of NT value of fetus and its normal reference range of women with different gestational weeks, maternal age, or fetal sex were observed. Pearson analysis was used to explore the correlation between NT value and gestational weeks and maternal age. Results: There were 3548 women completed fetal NT value measurement, which’s successful measurement rate was 96.7%. Among them, 3316 women were followed up, which’s success followed up rate was 93.5%, and the date of 3273 women with single-fetal pregnancy were finally included for analysis except to 43 women with abortion, dead fetal, or birth defects. The NT value of 3273 normal fetuses was in accordance with the normal distribution. The normal fetus NT value was 1.73±0.68 mm, which’s 95% reference range was 0.78-2.85 mm. The NT value of normal male fetus was significant more than that of female fetus. The fetal NT value of women over 35 years old was more than women egual to or less than 35 years old (all P＜0.05). Pearson correlation analysis showed that NT value was positively correlated with maternal age (r=0.419, P＜0.05), but had no correlation with gestational weeks (r=0.130, P＞0.05). Conclusion: The 95% reference range of fetal NT value of pregnant women with normal single-fetus pregnancy during the first trimester of pregnancy in Wuhan area is 0.78-2.85mm, and the NT value of elderly pregnant women increases.
|
|
|
|
|
|
|
|
|
