Abstract Preeclampsia (PE) is a specific systemic disease of pregnancy, which affects 35% of pregnant women. The incidence of PE of pregnant women in developing countries is as high as 10%. The basic pathological changes of PE are systemic small vasospasm, vascular endothelial damage, and local ischemia. However, the clinical treatment of PE is stagnation in the passive treatment after the onset of PE, and the prognosis is often poor. Therefore, the research on the early diagnosis markers of PE and prevent measurement before PE onset have become hot spots. This paper reviews the progress of early prediction and diagnosis of PE markers and the treatment methods before PE onset, so as to realize the early diagnosis, early prevention, and early treatment of PE.
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