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| The value of thrombelastography for guiding massive transfusion in postpartum hemorrhage treatment and its influence on the clinical prognosis |
| Baoji Maternal and Child Health Care Hospital, Shanxi Province, 721000 |
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Abstract Objective: To investigate the value of thromboelastography (TEG) for guiding massive transfusion (MT) in postpartum hemorrhage (PPH) treatment, and to study its influence on clinical prognosis. Methods: 47 puerpera with severe PPH were enrolled in this study from January 2016 to June 2018. TEG was used to detect coagulation function and guide MT treatment. The blood infusion before and after TEG detection and the blood transfusion based on different TEG parameters was observed. The clinical prognosis of puerpera was analyzed. Results: TEG detection showed that the patients with PPH had hypocoagulable state. In puerpera with Angle <53°, R value >10 min, and MA<37 mm, the amount of leukocyte suspension (LPRC), and the dosages of virus inactivated frozen plasma and cryoprecipitate had significantly increased (P<0.05). After adjusting the transfusion composition according to the TEG parameters, the R and K values had significantly shortened, the MA value, Angle value and CI value had been corrected, and the coagulation function had been improved significantly (P<0.05). These 47 puerpera had been successfully rescued without death. Conclusion: TEG detection can fully reflect the coagulation status of patients, and it has certain guiding significance for MT in the treatment of PPH, which may help to improve the clinical prognosis.
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