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| The influence of clinical features during the previous pre-eclampsia of pregnant women on their recurrence of pre-eclampsia |
| The Second People's Hospital of Nanyang, Henan Province, 473000 |
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Abstract Objective: To analyze the influence of clinical features during the previous pre-eclampsia of pregnant women on their pre-eclampsia recurrence rate and the gestational weeks of pre-eclampsia onset again. Methods: The clinical data of 155 pregnant women with a history of pre-eclampsia from January 2016 to December 2018 were collected retrospectively, and were divided in group A (women with pre-eclampsia again) and group B (women without pre-eclampsia again). The influence of clinical features during last pre-eclampsia of pregnant women on their pre-eclampsia recurrence rate and the different gestational weeks (＜34 and ≥34 gestational weeks) of pre-eclampsia onset again was analyzed. Results: There were statistically significant different in proprotions of the previous preeclampsia onset ≤28 gestational weeks, pregnancy interval ≥5 years, systolic blood pressure during pregnancy ≥160mmHg, diastolic blood pressure ≥110mmHg, and urine protein ≥2.0g/24h of women between group A and group B (P<0.05), but there were no difference in the gestational weeks for pregnancy termination of the previous pregnancy and the rate of serious complications of women between the two groups (P>0.05). Pre-eclampsia onset ≤28 gestational weeks, systolic blood pressure ≥160mmHg, diastolic blood pressure ≥110mmHg during the previous pregnancy were independent risk factors of recurrent preeclampsia (P< 0.05). Pre-eclampsia onset in 28-34 gestational weeks, pregnancy interval ≥5 years, and urine protein ≥2.0g/24h had no correlation with recurrent preeclampsia (P>0.05). There were statistically significant different in proprotions of the previous pre-eclampsia onset ≤28 gestational weeks, systolic blood pressure ≥160mmHg and diastolic blood pressure ≥110mmHg during last pregnancy between women with pre-eclampsia onset <34 gestational weeks and women with pre-eclampsia onset ≥34 gestational weeks (P<0.05), but there were no difference in the gestational weeks of pregnancy termination of last pregnancy, pregnancy interval ≥5 years, urine protein ≥2.0g/24h, and severe complications rate of women between the two groups (P>0.05). Conclusion: The early onset pre-eclampsia and severe hypertension occurrence during the previous pregnancy are the independent risk factors for the recurrence of pre-eclampsia, and also affect gestational weeks of pre-eclampsia onset again.
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