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| The correlation between serum AOPP and CysC levels during the third pregnancy trimester of women with early onset preeclampsia and their pregnancy outcomes#br# |
| 1.Qinghai Red Cross Hospital, Qinghai Province, 810000；2. Yangdong District People's Hospital of Yangjiang City, Guangdong Province, 529900 |
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Abstract Objective: To analyze the correlation between serum AOPP and CysC levels during the third pregnancy trimester of women with early onset preeclampsia and their pregnancy outcomes. Methods: 98 women with early onset preeclampsia were selected in study group from March 2016 to May 2018, and 98 healthy pregnant women were selected in control group during the same period. The AOPP and CysC levels from peripheral venous blood of women were detected. In the study group, the AOPP and CysC levels and pregnancy outcomes of women were compared among women with different severity preeclampsia. And the correlation analysis was performed. Results: The levels of AOPP and CysC of women in the study group were 76.17±9.33μmol/L and 1.39±0.37 mmol/L, which were significant higher than those (58.09±10.58μmol/L and 0.77±0.18 mmol/L) of women in the control group (P<0.05). The levels of AOPP and CysC of women with severe early onset preeclampsia were 81.37±9.75μmol/L and 1.62±0.51 mmol/L, which were significant higher than those (71.93±11.08μmol/L and 1.18±0.27 mmol/L) of women with mild early onset preeclampsia (P<0.05).The levels of AOPP and CysC of women with poor pregnancy outcomes were significant higher than those of women with good pregnancy outcomes (P<0.05).Correlation analysis showed that AOPP and CysC levels were significantly negatively correlated with pregnancy outcomes of women with early onset preeclampsia (P<0.05).Conclusion: The serum levels of AOPP and CysC of women with early onset preeclampsia are significant higher than those of healthy pregnant women. The AOPP and CysC levels are significantly negatively correlated with pregnancy outcomes, and the levels of AOPP and CysC are higher, the pregnancy outcomes are worser.
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