|
Abstract Objective: To investigate the effect of sodium hyaluronate combined with estradiol valerate for preventing uterine cavity adhesion and improving uterine recovery of women with missed abortion after uterine curettage. Methods: 372 women with missed abortion who underwent painless uterine curettage from March 2017 to March 2018 were selected and divided randomly divided into four groups (93 cases in each group) by random numbers table. After uterine curettage, the women in group A were given sodium hyaluronate only, the women in group B were given estradiol valerate only, the women in group C were given sodium hyaluronate combined with estradiol valerate, and the women in group D were not given any drugs. The situation of postoperative recovery and rates of adverse reactions and intrauterine adhesions were compared among the four groups. Results: The duration of vaginal bleeding and abdominal pain, and menstrual recovery time of women in group C were the shortest, and the total amount of vaginal bleeding was the lowest. The incidences of lower abdominal pain, vaginal secretions increased, and menstrual volume decreasing of women in group B and C were significant lower than those of women in group A and D. The incidence of uterine adhesions of women in group A was the highest, but that of women in group C was the lowest (P<0.05). In group B and C, there were several women with adverse reactions such as dizziness, nausea, breast swelling and pain, which all were mild and selfrelief. Conclusion: Sodium hyaluronate combined with estradiol valerate for treating women with missed abortion after uterine curettage can more effectively accelerate endometrial repaired and menstrual recovery, can prevent uterine adhesions, and has less adverse reactions, which can be tolerated well by women.
|
|
|
|
|
|
