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| Clinical effect of misoprostol in different administration for the cervical preparation of postmenopausal women before removing intrauterine device |
| Tongzhou District Maternal and Child Health Care and Family Planning Service Center, Nantong City, Jiangsu Province, 226300 |
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Abstract Objective: To study the clinical effect of misoprostol in different administration for the cervical preparation of postmenopausal women before removing intrauterine device (IUD). Methods: 168 postmenopausal and health women who voluntary required to remove IUD were divided into three groups. 3 hours before operation, the women in group A were given 0.6mg misoprostol oral, the women in group B were given 0.6mg misoprostol under the tongue, and the women in group C were given 0.6mg misoprostol in vagina. The clinical effect of women were observed and compared. Results: There were no statistical significant different in the cervical softening degree, intraoperative pain degree, operative time and intraoperative bleeding volume among the three groups (P>0.05). The rate of gastrointestinal side effects of women in group A was significant higher than that of women in group B and C (P<0.05), and the rates of chills, fever, headache, dizziness and itchy hands of women in group A and group B were significant higher than those of women in group C (P<0.05). Conclusion: The misoprostol given in vagina for the cervical preparation of postmenopausal women before removing IUD is effective and safety.
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