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| The influence of body mass index of women with polycystic ovary syndrome on their pregnancy outcomes after in vitro fertilization-embryo transfer |
| 1. Affiliated Hospital of Youjiang Nationalities Medical College, Baise City, Guangxi Zhuang Autonomous Region, 533000; 2. Guigang City People's Hospital |
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Abstract Objective: To investigate the influence of body mass index (BMI) of women with polycystic ovary syndrome (PCOS) on their pregnancy outcomes after in vitro fertilization-embryo transfer (IVF-ET). Methods: The data of 83 patients women with POCS who received IVF-ET treatment from February 2015 to December 2017 were retrospective analyzed. The women were divided into three groups according to their BMI, which included group A (25 cases with 18.5≤BMI< 23.0),group B (36 cases with 23.0≤BMI<25.0), and group C (22 cases with BMI≥ 25.0). The pregnancy outcomes of women were analyzed and compared among the three groups. Results: The levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH) and estradiol (E2) of women in group B and C were significant lower than those of women in group A (P<0.05). The days of follicle stimulating hormone used of women in group C was significant higher than that of women in group A, but the number of eggs obtained and the number of fertilizations were significant lower than those of women in group A (P<0.05). The number of high quality embryos of women in group C was significant less than that of women in group B and A (P<0.05). There were no significant different in the implantation rate, gestational age and abortion rate among the three groups (P>0.05). The pregnancy rate of women in group C was the lowest (P<0.05). The rate of gestational diabetes occurrence of women in group C was significant higher than that of women in group A and B (P<0.05), and the weight of neonates in group C and B was significant higher than that of neonates in group A (P<0.05). Conclusion: Overweight and obesity patients with PCOS during IVF-ET should use follicle stimulating hormone for longer time, but number of eggs or high-quality embryos obtained is less, which have higher risk of gestational diabetes and macrosomia, so it should be paid more attention to.
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