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| Clinical efficacy and prognosis of vaginal lesion clearance combined with uterine scar repair for treating women with type II cesarean scar pregnancy |
| The Fifth People's Hospital of Chengdu City, Sichuan Province, 611130 |
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Abstract To observe the clinical efficacy and prognosis of vaginal lesion clearance combined with uterine scar repair for treating women with type II cesarean scar pregnancy. Methods: 150 women with type II uterine scar pregnancy were selected as research objects from June 2013 to June 2015, and all of them were divided into control group (n=75) and obervation group (n=75) according to the random number table method. Women in obervation group were treated by vaginal lesion clearance combined with uterine scar repair, while women in control group were treated by uterine artery embolization combined with uterine curettage. The operation time, intraoperative bleeding volume, hospitalization time, menstrual recovery time, and treatment cost were compared between the two groups. Serum beta-hCG levels of all women were monitored before and after treatment. Results: There was no significant different in time of serum beta-hCG recovered to normal level between the two groups (t=0.934, P=0.152), but the amount of bleeding and treatment cost of women in obervation group were significant less than those of women in control group (t=6.314, 42.517; P=0.000, 0.000), and the hospital stay time, menstrual recovery time, and the time of beta-hCG recovered to normal level of women in obervation group were significant shorter than those of women in control group (t=5.931, 6.372, 15.633; P=0.000, 0.000, 0.000).The serum levels of beta-hCG of women in obervation group were significant lower than those of women in control group at 5 and 10 days after operation (t=12.853, 9.462; P=0.000, 0.000).The women in both groups were successfully operated, and no any woman had adverse reaction and complication during and after operation. The recurrence rate of uterine scar pregnancy of women in obervation group (1.3%) was significant lower than that of women in control group (12.0%), and the normal pregnancy rate of women (56.0%) was significant higher than that of women in control group (38.7%) (χ2=6.857, 4.520; P=0.009, 0.034). Conclusion: Vaginal lesion clearance combined with uterine scar repair for treating women with type II cesarean scar pregnancy has the characteristics of less iatrogenic trauma, rapid postoperative recovery, low medical costs, high safety and effectiveness, which can help to keep the fertility of women, reduce the risk of recurrence of scar pregnancy, so it has high clinical value to application.
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