|
|
|
| The influence of Kuntai capsule on serum levels of inflammation cytokines, sex hormone, and blood lipid of patients with premature ovarian failure |
| The Second Hospital of Shenzhen, Guangdong Province, 518035 |
|
|
|
|
Abstract To explore the influence of Kuntai capsule on serum levels of inflammation cytokines, sex hormone, and blood lipid of patients with premature ovarian failure. Methods: A total of 90 patients with premature ovarian failure were selected, and they were randomly divided into control group and observation group. The patients in control group were treated by pentanoic acid estradiol tablets for 3 months, and the patients in observation group were treated by Kuntai capsule for 3 months. The therapeutic effect was compared between the two groups. Results: After treatment, the effective rate of patients in observation group was 95.5%, which was significant higher than that (82.2%) of patients in control group (P<0.05). The serum levels of IL-21, TNF-α, FSH, LH, and LDL-C of patients in both groups had decreased significantly after treatment (P<0.05),but the levels of serum IL-1β, AMH, E2, HDL-C had were increased significantly (P<0.05). The levels of IL-21, TNFα, LDL-C of patients in treatment group were significant lower than those of women in control group(P<0.05), but the levels of AMH, E2, HDL-C of patients in treatment group were significant higher than those of women in control group(P<0.05).The levels of IL-1β, FSH and E2 had no significant different between the two groups (P>0.05). Conclusion: Kuntai capsule used to treat patients with premature ovarian failure has significant curative effect, which can improve the levels of inflammatory cytokines, sex hormones, and blood lipid of patients, so it is value to be popularized clinically.
|
|
|
|
|
|
|
|
|
