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| Analysis of vitamin D Level detection and its influence on pregnancy outcomes |
| The 411st Hospital of The Chinese People's Liberation Army, Shanghai, 200081 |
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Abstract To observe the level of 25-hydroxy vitamin D of pregnant women in Hongkou district of Shanghai, and to explore its influence on Pregnancy outcomes. Methods: 212 pregnant women from Hongkou district of Shanghai were selected. The vitamin D level of women, and the head circumference, chest circumference, weight, length and other indicators of their fetus were measured. The pregnancy outcomes and complications of all included women were followed up. Results: 91 (42.9%) women were vitamin D adequacy, 87 (41.0%) women were vitamin D inadequate, and 34 (16.0%) women were vitamin D lacking. There was no significant different in vitamin D level between pregnant women with different age, different pre-pregnancy BMI, women education level, and women income level (P>0.05). The average vitamin D level of pregnant women during spring and winter were significant lower than those of women during summer and autumn (P<0.05).The rates of abortion, fetal distress and bacterial vaginosis of women with Vitamin D deficiency was significant higher than those of women with Vitamin D adequacy and inadequate (P<0.05), but there were no significant different in the incidences of abortion, fetal distress and bacterial vaginosis between women with vitamin D adequate and inadequate (P>0.05). There were no significant different in rates of gestational diabetes, gestational hypertension, and cesarean section among the women with vitamin D deficiency, vitamin D inadequate, and vitamin D adequate (P>0.05). There was significant difference in fetal length and weight between women with different vitamin D level (P<0.05). The incidence of low birth weight neonatal of women with vitamin D deficiency was the highest, and that of women with vitamin D adequate was lowest (P<0.05). Conclusion: The pregnant women with vitamin D deficiency in Hongkou district of Shanghai is common and the lack of vitamin D can significantly increase the risk of adverse pregnancy outcomes and pregnancy complications. Therefore, it is very important to prevent vitamin D deficiency of pregnant women.
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