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Abstract Objective: To investigate the clinical efficacy and safety of prolonging the placement of Cook cervical dilatation balloon for promoting cervical ripening when induction of labor of fullterm pregnant women. Methods: From June 2016 to December 2017, 259 full-term pregnant women received cervical dilatation balloon placement in Shenzhen luohu district maternity and child health care hospital were included in this study. According to the time of the cervical dilatation balloon placement, all included women were divided into study group (Cook cervical dilatation balloon was placed for 16-20h, n=103) and control group (Cook cervical dilatation balloon was placed for 12h, n=156). The rate of cervical ripening, success rate of induced labor, delivery conditions, and outcomes of maternal and infant were compared between the two groups. Results: All women in both groups had been enhanced their cervical ripening in varying degrees. The efficiency of enhanced cervical ripening of women in study group was significant higher than that of women in control group (P<0.05). The duration of the first stage of labor of women in study group was significant shorter than that of women in control group (P<0.05). The induced labor rate of women in study group was significant higher than that of women in control group (P<0.05). And the cesarean delivery rate of women in study group was significant lower than that of women in control group (P<0.05). There were no statistically significant different in rates of acute chorioamnionitis, puerperal infection, postpartum hemorrhage, cervical lacerate, fetal distress, and neonatal asphyxia between the two groups (P>0.05). Conclusion: Prolonging the placement of Cook cervical dilatation balloon for induction of labor of fullterm pregnant women can better promote cervical ripening, can reduce the cesarean delivery rate. It is safety and effective without increasing maternal and fetal complications, so it is worthy of clinical application.
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