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| Clinical analysis of the way of in vitro fertilization for patients with low oocytes retrieved |
| TianJin Medical University, Tianjin |
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Abstract Objective: To explore the clinical outcomes of different ways of in vitro fertilization (IVF) or intracytoplasmic sperm injectionon(ICSI) for patients with a little oocytes retrieved cycles. Methods: 190 cycles with no more than 3 oocytes retrieved and used normal semen between January 2013 and June 2016 were retrospective analyzed. The clinical outcomes of patients in IVF group(n=97) and in ICSI group(n=93) were compared. Results：Basal characteristics were similar in both group including the normal fertilization rate (61.6％ vs 59.9%), the cleavage rate (91.8% vs973%) , the high quality embryo rate(67.9% vs 66.1%), the complete fertilization failure rate (11.3% vs 20.4%), the available embryto rate (91.1% vs 94.5% ) , the cycle cancellation rate (35.1% vs 28.0%), the implantation rate (321% vs 20.8%), the pregnancy rate (46.0% vs 27.3%), the clinical live birth rate (83.3% vs 60.0%), the cumulative pregnancy rate (35.7% vs 24.1%) and the cumulative birth rate (32.1% vs 18.5), which all had no significant difference(P＞ 0.05). However, there was significant difference in the multiple precision number (PN) rate (14.1% vs 1.6%) (P<0.05). Conclusion: When retrieved oocyte number is equal to or less 3, and patients has no ICSI indications, selecting ICSI can reduce the multiple PN rate, but the other clinical outcomes have no significant improvement.
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