|
|
|
| Value of applications of fourquadrant biopsy by colposcopy for diagnosing cervical cancer |
| Department of Obstetrics and Gynecology, Affiliated Hospital of Nankai University, Tianjin, 300222 |
|
|
|
|
Abstract To investigate the application values of colposcopic fourquadrant biopsy for diagnosing cervical cancer. Methods: A retrospective study was conducted to analyze the clinical data of 150 patients with positive result by cervical thinprep cytologic test (TCT) from January 2015 to June 2016 in Affiliated Hospital of Nankai University. All patients were further checked by colposcopy checked, cervical fourquadrant biopsy under colposcopy or suspicious lesions biopsy under colposcopy, and tissue from biopsy was further pathological determined. The patients with pathological positive result of biopsy tissue had been operated for removing lesions tissue. And postoperative pathological result was the final diagnosis. Results: 48 cases (32.0%) had negative results and 102 cases (68.0%) had positive results by colposcopy checked. The negative rate of postoperative pathology was 36.7% (55 cases), and 95 cases (63.3%) were positive pathological results. The coincidence rate diagnosed by colposcopic biopsy and postoperative pathology was 87.3%. Among them, the coincidence rate of diagnosed LSIL, HSIL and invasive carcinoma by fourquadrant biopsy under colposcopy and by postoperative pathology were 71.4%, 81.6% and 100%, respectively. The coincidence rate of diagnosed LSIL, HSIL and invasive carcinoma by suspicious lesions biopsy under colposcopy and postoperative pathology were 68.2%, 73.7%, 88.2%, respectively. The rate of diagnostic accuracy of cervical cancer was higher than that of LSIL and HSIL (P<0.05). The coincidence rate of diagnosis LSIL and above LSIL by four quadrant biopsy under colposcopy was higher than that by suspicious lesions biopsy under colposcopy (P<0.05). The sensitivity, accuracy and positive predictive value (91.7%, 98.0%, 100.0%) of fourquadrant biopsy under colposcopy for diagnosing cervical cancer were significantly higher than those of suspicious lesions biopsy under colposcopy (P<0.05). Conclusion: Fourquadrant biopsy under colposcopy has great value in the early screening of cervical cancer, which can improve the detection rate and diagnostic accuracy of cervical cancer.
|
|
|
|
|
|
|
|
|
