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Abstract To explore the effect of different ovarian stimulated protocols on pregnant and delivery outcomes of women experienced in vitro fertilization and embryo transplantation (IVFET). Methods：1104 women who experienced IVFET because of their fallopian tubal disease were included and randomly assigned into long protocol group or short protocol group based on these women were given different ovarian stimulated protocol. The rate of clinical pregnancy, pregnant loss, and livebirth delivery of women were compared between the two groups. Results: The rate of clinical pregnancy(45.1%) and rate of livebirth delivery (35.7%) of women in long protocol group were significant higher than those of women(33.9%, 24.8%) in short protocol group (P＜0.01), but there were no significant difference in the rate of preterm birth and ovarian hyperstimulation between the two groups(P>0.05). The rate of double fetus and single fetal were 61.1% and 5.5% in long protocol group, and the rate of double fetus and single fetus were 45.2% or 7.9% in short protocol group，and there were significant difference in rate of double fetus and single fetus between the two groups(P<0.01). The rate of preterm birth in women with double fetus in both groups was significant higher than that of single fetus (P<0.01). There were no significant difference in deliver ways and fetal sex ratio of women between the two groups (P>0.05). Conclusion: The long GnRHa protocol for IVFET can improve rate of clinical pregnancy and livebirth delivery, and can decrease the loss of pregnancy. The single fetal pregnancy is better than multiple fetal pregnancy, so it is very important for single embryo transfer.
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